2025
Decline in Community-Acquired Alveolar Pneumonia Positive for Respiratory Syncytial Virus in Hospitalized Children Following Implementation of Pneumococcal Conjugate Vaccine (PCV) in Israel
Dagan R, van der Beek B, Grupel T, Greenberg D, Keren-Naus A, Ben-Shimol S, Weinberger D. Decline in Community-Acquired Alveolar Pneumonia Positive for Respiratory Syncytial Virus in Hospitalized Children Following Implementation of Pneumococcal Conjugate Vaccine (PCV) in Israel. Clinical Infectious Diseases 2025, ciaf102. PMID: 40052957, DOI: 10.1093/cid/ciaf102.Peer-Reviewed Original ResearchPneumococcal conjugate vaccineImpact of pneumococcal conjugate vaccinesConjugate vaccineCommunity-acquired alveolar pneumoniaPneumococcal conjugate vaccine implementationImplementation of pneumococcal conjugate vaccinesRespiratory syncytial virusAnnual hospitalization rateCommunity-acquiredAlveolar pneumoniaSyncytial virusPCV13 implementationAnnual incidenceYoung childrenHospitalization ratesIncidenceRSVMonthsVaccineChildrenEpisodesRegression modelsSynergistic rolePCV13Binomial regression models
2024
Estimated Population-Level Impact of Pneumococcal Conjugate Vaccines Against All-Cause Pneumonia Mortality Among Unvaccinated in 5 Latin American Countries
Prunas O, Shioda K, Toscano C, Bastias M, Valenzuela-Bravo M, Tito J, Warren J, Weinberger D, de Oliveira L. Estimated Population-Level Impact of Pneumococcal Conjugate Vaccines Against All-Cause Pneumonia Mortality Among Unvaccinated in 5 Latin American Countries. The Journal Of Infectious Diseases 2024, 230: e768-e776. PMID: 38502711, PMCID: PMC11481321, DOI: 10.1093/infdis/jiae144.Peer-Reviewed Original ResearchAll-cause pneumoniaPneumonia deathsPneumonia mortalityAge groupsPneumococcal conjugate vaccineProportion of IPD casesInvasive pneumococcal diseaseMulti-country studyIPD casesOlder age groupsPopulation-level impactMortality dataYears of ageInvasive pneumococcal disease casesConjugate vaccinePneumococcal conjugate vaccine introductionEffect of pneumococcal conjugate vaccinesTemporal trendsImpact of pneumococcal conjugate vaccinesUnvaccinated age groupsMortalityEvaluate changesPost-vaccination periodVaccine serotypesNo significant changes
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